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AHRQ casts wide net of HAI research projects
Hospital projects include SSIs
The federal Agency for Healthcare Research and Quality's (AHRQ) $34 million initiative to prevent health care associated infections (HAIs) includes the following hospital-based projects. Look to future issues of Hospital Infection Control & Prevention for full findings and analysis of these projects.
Effect of the use of universal glove and gowning on HAI rates: This project will determine the effectiveness of universal glove and gowning procedures in reducing HAI rates in intensive care units (ICUs). Objectives include:
Evaluating Clostridium difficile infection in hospitalized patients: This project will evaluate the extent to which hospital-level antibiotic and gastric acid suppressant usage patterns, infection prevention and control, and pharmacy policies predict CDI occurrence; develop and compare various approaches to risk adjustment to identify hospitals with higher- or lower-than-expected CDI rates; and identify facilitators and barriers to implementation of best practices for CDI prevention.
National implementation of comprehensive unit-based safety program (CUSP) to reduce central line-associated blood stream infections (CLABSIs): This project expands the previously funded project to reduce CLABSI to allow participation by all units and in all hospitals that wish to reduce CLABSI rates. Objectives include:
Central venous catheter-related blood stream infections in pediatric cancer: This project will perform a study comparing the impact of using a specialty team of nurses providing evidence-based central venous catheter care versus the use of assigned bedside nurses on reducing central venous catheter-related blood stream infections among pediatric oncology patients.
Translating comparative effectiveness research results from ICU study to improve outcomes in cardiac surgery: This project will implement and evaluate the impact of CUSP on rates of SSIs and cardiac operating room safety culture; on rates of CLABSI, ventilator-associated pneumonia, and safety culture in cardiac surgical ICUs; on errors associated with handoffs from the ICU to the floor and discharge from the hospital; and on 30-day mortality, hospital readmissions, and hospital length of stay in cardiac operating rooms, ICUs, and floors compared to passive feedback of outcome data.
Quality of care and outcomes of health care-associated pneumonia: This project will characterize the clinical features and outcomes of patients hospitalized with health care-associated pneumonia compared to patients hospitalized with community-acquired pneumonia. It will refine and validate an inpatient pneumonia mortality model using hospital claims data and assess adherence to antibiotic prescribing guidelines in the setting of health care-associated pneumonia and identify factors associated with guideline-concordant treatment.
Optimizing pre-operative surgical antibiotic prophylaxis: This project aims to determine whether a pre-operative antibiotic prophylaxis algorithm that includes the use (including selective use) of antibiotics shown to be effective against resistant gram-positive organisms is effective in reducing the number of SSIs attributable to resistant gram-positive organisms. Objectives include: